Tunable pharmacokinetics: modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment.
Olafsen, Tove
Tunable pharmacokinetics: modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment. [electronic resource] - Nature protocols 2006 - 2048-60 p. digital
Publication Type: Journal Article
1750-2799
10.1038/nprot.2006.322 doi
Animals
Antibodies--genetics
Half-Life
Isotope Labeling--methods
Mutagenesis, Site-Directed--methods
Receptors, Fc--metabolism
Recombinant Proteins--isolation & purification
Tunable pharmacokinetics: modifying the in vivo half-life of antibodies by directed mutagenesis of the Fc fragment. [electronic resource] - Nature protocols 2006 - 2048-60 p. digital
Publication Type: Journal Article
1750-2799
10.1038/nprot.2006.322 doi
Animals
Antibodies--genetics
Half-Life
Isotope Labeling--methods
Mutagenesis, Site-Directed--methods
Receptors, Fc--metabolism
Recombinant Proteins--isolation & purification