Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine.

Sicouri, Serge

Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine. [electronic resource] - Heart rhythm May 2007 - 638-47 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1547-5271

10.1016/j.hrthm.2006.12.046 doi


3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester--adverse effects
Acetanilides--pharmacology
Action Potentials--drug effects
Analysis of Variance
Animals
Anti-Arrhythmia Agents--pharmacology
Calcium Channel Agonists--adverse effects
Disease Models, Animal
Dogs
Electrocardiography
Endocardium--cytology
Enzyme Inhibitors--pharmacology
Heart Ventricles--cytology
Long QT Syndrome--drug therapy
Myocytes, Cardiac--drug effects
Patch-Clamp Techniques
Pericardium--cytology
Piperazines--pharmacology
Ranolazine
Tachycardia, Ventricular--chemically induced
Torsades de Pointes--chemically induced
Ventricular Premature Complexes--chemically induced