Absolute configuration of glycerol derivatives. 4. Synthesis and pharmacological activity of chiral 2-alkylaminomethylbenzodioxans, competitive alpha-adrenergic antagonists.

Nelson, W L

Absolute configuration of glycerol derivatives. 4. Synthesis and pharmacological activity of chiral 2-alkylaminomethylbenzodioxans, competitive alpha-adrenergic antagonists. [electronic resource] - Journal of medicinal chemistry Jul 1977 - 880-5 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm00217a002 doi


Adrenergic alpha-Antagonists--chemical synthesis
Animals
Aorta--drug effects
Circular Dichroism
Dioxanes--chemical synthesis
Dioxins--chemical synthesis
In Vitro Techniques
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Conformation
Muscle Contraction--drug effects
Muscle, Smooth--drug effects
Rabbits
Stereoisomerism