Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type.

Niemann, Catherin

Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type. [electronic resource] - Cancer research Apr 2007 - 2916-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472

10.1158/0008-5472.CAN-06-3427 doi


9,10-Dimethyl-1,2-benzanthracene
Adenocarcinoma, Sebaceous--chemically induced
Animals
Cell Transformation, Neoplastic--chemically induced
Cocarcinogenesis
Cyclin-Dependent Kinase Inhibitor p21--metabolism
Epidermis--drug effects
Female
Genes, ras
Lymphoid Enhancer-Binding Factor 1--genetics
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Mice, Transgenic
Mutation
Sebaceous Gland Neoplasms--chemically induced
Skin Neoplasms--chemically induced
Tetradecanoylphorbol Acetate
Tumor Suppressor Protein p53--metabolism