Targeted deletion of class A macrophage scavenger receptor increases the risk of cardiac rupture after experimental myocardial infarction.

Tsujita, Kenichi

Targeted deletion of class A macrophage scavenger receptor increases the risk of cardiac rupture after experimental myocardial infarction. [electronic resource] - Circulation Apr 2007 - 1904-11 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4539

10.1161/CIRCULATIONAHA.106.671198 doi


Animals
Cells, Cultured--drug effects
Crosses, Genetic
Cytokines--biosynthesis
Enzyme Induction
Gene Deletion
Heart Rupture--etiology
Interleukin-10--analysis
Lipoproteins, LDL--pharmacology
Macrophages, Peritoneal--drug effects
Male
Matrix Metalloproteinase 2--biosynthesis
Matrix Metalloproteinase 9--biosynthesis
Mice
Mice, Inbred C57BL
Mice, Knockout
Myocardial Infarction--complications
Myocardium--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Scavenger Receptors, Class A--deficiency
Tissue Inhibitor of Metalloproteinase-1--biosynthesis
Tissue Inhibitor of Metalloproteinases--biosynthesis
Tumor Necrosis Factor-alpha--biosynthesis
Ventricular Remodeling--physiology
Tissue Inhibitor of Metalloproteinase-4