F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. III. Activity in models of cognition and negative symptoms.

Depoortère, R

F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. III. Activity in models of cognition and negative symptoms. [electronic resource] - British journal of pharmacology May 2007 - 266-77 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-1188

10.1038/sj.bjp.0707160 doi


Amnesia--physiopathology
Animals
Antipsychotic Agents--pharmacology
Behavior, Animal--drug effects
Benzofurans--pharmacology
Benzylamines--pharmacology
Cognition Disorders--chemically induced
Cyclopentanes--pharmacology
Dopamine Agonists--pharmacology
Dopamine Antagonists--pharmacology
Dopamine D2 Receptor Antagonists
Dose-Response Relationship, Drug
Male
Models, Animal
Phencyclidine
Rats
Rats, Sprague-Dawley
Receptors, Dopamine D3--antagonists & inhibitors
Receptors, Dopamine D4--agonists
Reflex--drug effects
Reflex, Startle--drug effects
Serotonin 5-HT1 Receptor Agonists
Serotonin 5-HT1 Receptor Antagonists
Serotonin Receptor Agonists--pharmacology