Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase.

Park, Yong Seek

Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology Jun 2007 - 1319-25 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4636

10.1161/ATVBAHA.106.132837 doi


Acetophenones--pharmacology
Acrolein--metabolism
Animals
Atherosclerosis--etiology
Benzopyrans--pharmacology
Cells, Cultured
Cyclic AMP Response Element-Binding Protein--metabolism
Cyclooxygenase 2--biosynthesis
Dinoprostone--metabolism
Dose-Response Relationship, Drug
Endothelial Cells--drug effects
Enzyme Induction--drug effects
Humans
Imidazoles--pharmacology
Lung--drug effects
Male
Membrane Proteins--biosynthesis
Mice
Mice, Inbred C57BL
Phosphorylation
Promoter Regions, Genetic--drug effects
Protein Kinase C-delta--antagonists & inhibitors
Protein Kinase Inhibitors--pharmacology
Pyridines--pharmacology
RNA, Messenger--biosynthesis
Smoking--adverse effects
Time Factors
Transcription, Genetic--drug effects
Umbilical Veins--cytology
p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors