Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.
Fisher, Craig D
Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Jun 2007 - 995-1000 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
0090-9556
10.1124/dmd.106.014340 doi
Allyl Compounds--pharmacology
Animals
Aryl Hydrocarbon Hydroxylases--genetics
Constitutive Androstane Receptor
Cytochrome P-450 CYP2B1--genetics
Cytochrome P-450 CYP2B6
Cytochrome P450 Family 2
Disulfides--pharmacology
Female
Herb-Drug Interactions
Humans
Liver--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
NAD(P)H Dehydrogenase (Quinone)--genetics
NADPH Dehydrogenase--genetics
NF-E2-Related Factor 2--deficiency
Oxidoreductases, N-Demethylating--genetics
RNA, Messenger--metabolism
Rats
Rats, Wistar
Receptors, Cytoplasmic and Nuclear--deficiency
Steroid Hydroxylases--genetics
Sulfides--pharmacology
Transcription Factors--deficiency
Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Jun 2007 - 995-1000 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
0090-9556
10.1124/dmd.106.014340 doi
Allyl Compounds--pharmacology
Animals
Aryl Hydrocarbon Hydroxylases--genetics
Constitutive Androstane Receptor
Cytochrome P-450 CYP2B1--genetics
Cytochrome P-450 CYP2B6
Cytochrome P450 Family 2
Disulfides--pharmacology
Female
Herb-Drug Interactions
Humans
Liver--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
NAD(P)H Dehydrogenase (Quinone)--genetics
NADPH Dehydrogenase--genetics
NF-E2-Related Factor 2--deficiency
Oxidoreductases, N-Demethylating--genetics
RNA, Messenger--metabolism
Rats
Rats, Wistar
Receptors, Cytoplasmic and Nuclear--deficiency
Steroid Hydroxylases--genetics
Sulfides--pharmacology
Transcription Factors--deficiency