Parallel synthesis and SAR study of novel oxa-steroids as potent and selective progesterone receptor antagonists.

Kang, Fu-An

Parallel synthesis and SAR study of novel oxa-steroids as potent and selective progesterone receptor antagonists. [electronic resource] - Bioorganic & medicinal chemistry letters May 2007 - 2531-4 p. digital

Publication Type: Journal Article

0960-894X

10.1016/j.bmcl.2007.02.013 doi


Animals
Cell Line, Tumor
Chemistry, Pharmaceutical--methods
Complement C3--metabolism
Drug Design
Female
Humans
Mifepristone--pharmacology
Models, Chemical
Protein Binding
Rats
Receptors, Glucocorticoid--antagonists & inhibitors
Receptors, Progesterone--antagonists & inhibitors
Steroids--chemistry
Structure-Activity Relationship