Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF-kappaB-dependent pathway.

Khan, Nooruddin

Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF-kappaB-dependent pathway. [electronic resource] - International immunology Apr 2007 - 477-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0953-8178

10.1093/intimm/dxm012 doi


Animals
Antibodies, Monoclonal--immunology
B7-1 Antigen--immunology
B7-2 Antigen--immunology
Cell Line
Cell Line, Transformed
Cell Line, Tumor
Cell Survival--drug effects
Culture Media, Conditioned--pharmacology
Cytotoxicity, Immunologic--drug effects
Escherichia coli--cytology
Gene Expression--drug effects
I-kappa B Proteins--genetics
Immunity, Innate--drug effects
Immunoglobulin Fab Fragments--pharmacology
Interferon-gamma--pharmacology
Lipopolysaccharides--pharmacology
Macrophages--drug effects
Mice
Mice, Inbred BALB C
Microbial Viability--drug effects
NF-KappaB Inhibitor alpha
NF-kappa B--metabolism
Reactive Oxygen Species--metabolism
Transfection
Tumor Necrosis Factor-alpha--genetics