Evidence for the involvement of several cytochromes P-450 in the first steps of caffeine metabolism by human liver microsomes.

Berthou, F

Evidence for the involvement of several cytochromes P-450 in the first steps of caffeine metabolism by human liver microsomes. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals - 561-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0090-9556


Adult
Biotransformation
Blotting, Western
Caffeine--metabolism
Cytochrome P-450 CYP1A2
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--metabolism
Dealkylation
Female
Humans
In Vitro Techniques
Male
Microsomes, Liver--enzymology
Middle Aged
Mixed Function Oxygenases--metabolism
Oxidation-Reduction
Oxidoreductases--antagonists & inhibitors
Phenacetin--pharmacology
Theophylline--metabolism