Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses.

Connor, John H

Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses. [electronic resource] - Virology May 2007 - 109-19 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0042-6822

10.1016/j.virol.2006.12.026 doi


Animals
Antiviral Agents--pharmacology
Avulavirus--drug effects
Benzoquinones--pharmacology
Cell Line
Cricetinae
DNA-Directed RNA Polymerases--metabolism
HSP90 Heat-Shock Proteins--antagonists & inhibitors
HeLa Cells
Humans
La Crosse virus--drug effects
Lactams, Macrocyclic--pharmacology
Macrolides--pharmacology
Proteasome Endopeptidase Complex--metabolism
RNA Interference
RNA Viruses--drug effects
RNA, Small Interfering
RNA-Dependent RNA Polymerase--metabolism
Vesicular stomatitis Indiana virus--drug effects
Viral Proteins--metabolism
Virus Replication--drug effects