Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism.

Collier, Timothy J

Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism. [electronic resource] - Neurobiology of disease Apr 2007 - 56-65 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0969-9961

10.1016/j.nbd.2006.11.013 doi


Aging--physiology
Animals
Behavior, Animal--drug effects
Brain--pathology
Chromatography, High Pressure Liquid
Dopamine--metabolism
Female
Immunohistochemistry
MPTP Poisoning--pathology
Macaca mulatta
Motor Activity--drug effects
Neostriatum--growth & development
Parkinson Disease, Secondary--chemically induced
Substantia Nigra--growth & development
Tyrosine 3-Monooxygenase--metabolism