NADPH oxidase inhibition prevents cocaine-induced up-regulation of xanthine oxidoreductase and cardiac dysfunction.

Isabelle, Marc

NADPH oxidase inhibition prevents cocaine-induced up-regulation of xanthine oxidoreductase and cardiac dysfunction. [electronic resource] - Journal of molecular and cellular cardiology Feb 2007 - 326-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2828

10.1016/j.yjmcc.2006.11.011 doi


Acetophenones--pharmacology
Allopurinol--pharmacology
Anesthetics, Local--toxicity
Animals
Cardiomyopathies--chemically induced
Cocaine--toxicity
Enzyme Inhibitors--pharmacology
Male
Myocardium--enzymology
NADPH Oxidases--antagonists & inhibitors
Rats
Rats, Wistar
Reactive Oxygen Species--metabolism
Up-Regulation--drug effects
Ventricular Dysfunction, Left--chemically induced
Xanthine Dehydrogenase--biosynthesis