Modulation of P2X7 receptor functions by polymyxin B: crucial role of the hydrophobic tail of the antibiotic molecule.

Ferrari, D

Modulation of P2X7 receptor functions by polymyxin B: crucial role of the hydrophobic tail of the antibiotic molecule. [electronic resource] - British journal of pharmacology Feb 2007 - 445-54 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-1188

10.1038/sj.bjp.0706994 doi


Adenosine Triphosphate--physiology
Anti-Bacterial Agents--chemistry
Blotting, Western
Calcium--metabolism
Cell Fusion
Cell Line
Cell Membrane--drug effects
Cell Membrane Permeability--drug effects
Cell Shape--drug effects
Cytoplasm--drug effects
Green Fluorescent Proteins--metabolism
Humans
L-Lactate Dehydrogenase--metabolism
Macrophages--drug effects
Polymyxin B--analogs & derivatives
Porosity
Receptors, Purinergic P2--drug effects
Receptors, Purinergic P2X7
Structure-Activity Relationship