Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer.

Fernández-Majada, V

Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jan 2007 - 276-81 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0027-8424

10.1073/pnas.0606476104 doi


Animals
Cell Line
Cell Nucleus--enzymology
Colorectal Neoplasms--genetics
Enzyme Activation
Gene Expression Regulation, Neoplastic
Humans
I-kappa B Kinase--physiology
Male
Mice
NF-kappa B--physiology
Nitriles--pharmacology
Phosphorylation
Receptors, Notch--physiology
Repressor Proteins--physiology
Sulfones--pharmacology