A comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) of anthranilamide derivatives that are multidrug resistance modulators.

Labrie, Philippe

A comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) of anthranilamide derivatives that are multidrug resistance modulators. [electronic resource] - Journal of medicinal chemistry Dec 2006 - 7646-60 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm060239b doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics
Daunorubicin--metabolism
Drug Design
Drug Resistance, Multiple
Humans
Inhibitory Concentration 50
Models, Chemical
Models, Molecular
Molecular Conformation
Molecular Structure
Quantitative Structure-Activity Relationship
ortho-Aminobenzoates--chemistry