A negative feedback signaling network underlies oncogene-induced senescence.

Courtois-Cox, Stéphanie

A negative feedback signaling network underlies oncogene-induced senescence. [electronic resource] - Cancer cell Dec 2006 - 459-72 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1535-6108

10.1016/j.ccr.2006.10.003 doi


Animals
Cells, Cultured
Cellular Senescence
Feedback
Genes, Neurofibromatosis 1--physiology
Genes, Retinoblastoma--physiology
Genes, p53--physiology
Genes, ras--physiology
Humans
Mice
Neoplasms--genetics
Phosphatidylinositol 3-Kinases--physiology
Signal Transduction--physiology
Stem Cells--pathology
raf Kinases--physiology