Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor alpha-induced activation of transcription factor nuclear factor kappaB.

Heynekamp, Justin J

Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor alpha-induced activation of transcription factor nuclear factor kappaB. [electronic resource] - Journal of medicinal chemistry Nov 2006 - 7182-9 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm060630x doi


Antioxidants--chemical synthesis
Cell Line
Combinatorial Chemistry Techniques
Cyclooxygenase 2 Inhibitors--chemical synthesis
Humans
NF-kappa B--metabolism
Resveratrol
Stereoisomerism
Stilbenes--chemical synthesis
Structure-Activity Relationship
Tumor Necrosis Factor-alpha--antagonists & inhibitors