Bioavailability enhancement of poorly water soluble and weakly acidic new chemical entity with 2-hydroxy propyl-beta-cyclodextrin: selection of meglumine, a polyhydroxy base, as a novel ternary component.

Basavaraj, S

Bioavailability enhancement of poorly water soluble and weakly acidic new chemical entity with 2-hydroxy propyl-beta-cyclodextrin: selection of meglumine, a polyhydroxy base, as a novel ternary component. [electronic resource] - Pharmaceutical development and technology 2006 - 443-51 p. digital

Publication Type: Journal Article

1083-7450

10.1080/10837450600770577 doi


2-Hydroxypropyl-beta-cyclodextrin
Acids
Biological Availability
Drug Carriers--chemistry
Hydrogen-Ion Concentration
Meglumine--pharmacokinetics
Pyrazoles--administration & dosage
Solubility
Sulfonamides--administration & dosage
Thermodynamics
Water
beta-Cyclodextrins--chemistry