Novel beta-lactam derivatives: potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome.

Imbach, Patricia

Novel beta-lactam derivatives: potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2007 - 358-62 p. digital

Publication Type: Journal Article

0960-894X

10.1016/j.bmcl.2006.10.047 doi


Chymotrypsin--antagonists & inhibitors
Crystallography, X-Ray
Drug Design
Humans
Models, Molecular
Peptides--chemistry
Proteasome Inhibitors
Structure-Activity Relationship
Trypsin Inhibitors--chemical synthesis
beta-Lactams--chemical synthesis