Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells.

Catalano, Maria G

Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells. [electronic resource] - The Journal of endocrinology Nov 2006 - 465-72 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-0795

10.1677/joe.1.06970 doi


Acetylation
Antigens, Neoplasm--analysis
Antineoplastic Agents--therapeutic use
Apoptosis
Carcinoma--drug therapy
Caspase 3--metabolism
Cell Cycle--drug effects
Cell Differentiation--drug effects
Cell Line, Tumor
DNA Fragmentation
DNA Topoisomerases, Type II--analysis
DNA-Binding Proteins--analysis
Doxorubicin--therapeutic use
Histone Deacetylase Inhibitors
Histones--metabolism
Humans
RNA, Messenger--analysis
Thyroid Neoplasms--drug therapy
Valproic Acid--therapeutic use