Structural basis for the platelet-collagen interaction: the smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycine-proline-hydroxyproline triplets.

Smethurst, Peter A

Structural basis for the platelet-collagen interaction: the smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycine-proline-hydroxyproline triplets. [electronic resource] - The Journal of biological chemistry Jan 2007 - 1296-304 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M606479200 doi


Binding Sites--physiology
Blood Platelets--metabolism
Collagen--chemistry
Cross-Linking Reagents--chemistry
Glycine--metabolism
Humans
Hydroxyproline--metabolism
Membrane Proteins--chemistry
Peptide Fragments--chemistry
Phosphorylation
Platelet Adhesiveness--physiology
Platelet Aggregation--physiology
Platelet Membrane Glycoproteins--chemistry
Proline--metabolism
Protein Binding--physiology
Protein Structure, Tertiary
Recombinant Proteins--chemistry
Signal Transduction--physiology
Structure-Activity Relationship
Tyrosine--metabolism