Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets.
Dandapani, Sivaraman
Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets. [electronic resource] - The Journal of organic chemistry Nov 2006 - 8934-45 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
0022-3263
10.1021/jo061758p doi
Aza Compounds--chemical synthesis
Catalysis
Combinatorial Chemistry Techniques--methods
Crystallography, X-Ray
Diketopiperazines
Drug Evaluation, Preclinical
Models, Molecular
Molecular Conformation
Pipecolic Acids--chemistry
Piperazines--chemical synthesis
Receptors, G-Protein-Coupled--antagonists & inhibitors
Stereoisomerism
Structure-Activity Relationship
Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets. [electronic resource] - The Journal of organic chemistry Nov 2006 - 8934-45 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
0022-3263
10.1021/jo061758p doi
Aza Compounds--chemical synthesis
Catalysis
Combinatorial Chemistry Techniques--methods
Crystallography, X-Ray
Diketopiperazines
Drug Evaluation, Preclinical
Models, Molecular
Molecular Conformation
Pipecolic Acids--chemistry
Piperazines--chemical synthesis
Receptors, G-Protein-Coupled--antagonists & inhibitors
Stereoisomerism
Structure-Activity Relationship