Mitochondrial isocitrate dehydrogenase protects human neuroblastoma SH-SY5Y cells against oxidative stress.

Kim, Sun J

Mitochondrial isocitrate dehydrogenase protects human neuroblastoma SH-SY5Y cells against oxidative stress. [electronic resource] - Journal of neuroscience research Jan 2007 - 139-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0360-4012

10.1002/jnr.21106 doi


Antioxidants--pharmacology
Caspase 3--metabolism
Cell Death--drug effects
Cell Line, Tumor
DNA Fragmentation--drug effects
Dose-Response Relationship, Drug
Drug Interactions
Enzyme Activation--drug effects
Enzyme Inhibitors--pharmacology
Glutathione--metabolism
Humans
Indoles
Isocitrate Dehydrogenase--pharmacology
Membrane Potential, Mitochondrial--drug effects
Mitochondria--drug effects
NADP--metabolism
Neuroblastoma
Oxidative Stress--drug effects
RNA, Messenger--biosynthesis
Reactive Oxygen Species--metabolism
Reverse Transcriptase Polymerase Chain Reaction--methods
S100 Proteins--metabolism
Staurosporine--pharmacology
Transfection--methods