Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells.

Whitley, Brandi R

Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells. [electronic resource] - Gynecologic oncology Feb 2007 - 470-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0090-8258

10.1016/j.ygyno.2006.08.048 doi


Cell Line, Tumor
Cell Movement--drug effects
Chromones--pharmacology
Female
Humans
Insulin--pharmacology
Insulin-Like Growth Factor I--pharmacology
Morpholines--pharmacology
Ovarian Neoplasms--enzymology
Phosphatidylinositol 3-Kinases--metabolism
Phosphoinositide-3 Kinase Inhibitors
Plasminogen Activator Inhibitor 1--biosynthesis
Proto-Oncogene Proteins c-akt--genetics
RNA, Small Interfering--genetics
Signal Transduction
Transfection
Urokinase-Type Plasminogen Activator--antagonists & inhibitors