Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1.

Huang, Chin-Shiu

Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1. [electronic resource] - The Journal of nutritional biochemistry Jul 2007 - 449-56 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0955-2863

10.1016/j.jnutbio.2006.08.007 doi


Anticarcinogenic Agents--pharmacology
Carcinoma, Hepatocellular
Carotenoids--pharmacokinetics
Cell Line, Tumor
Cell Survival--drug effects
Enzyme-Linked Immunosorbent Assay
Gene Expression Regulation, Enzymologic--drug effects
Humans
Liver Neoplasms
Lycopene
Matrix Metalloproteinase 9--genetics
NF-kappa B--metabolism
Neoplasm Invasiveness--prevention & control
RNA, Neoplasm--genetics
Reactive Oxygen Species--metabolism
Receptor, IGF Type 1--drug effects
Reverse Transcriptase Polymerase Chain Reaction