Determination of pulmonary irritant threshold concentrations of hexamethylene-1,6-diisocyanate (HDI) prepolymers by bronchoalveolar lavage in acute rat inhalation studies according to TRGS 430.

Ma-Hock, L

Determination of pulmonary irritant threshold concentrations of hexamethylene-1,6-diisocyanate (HDI) prepolymers by bronchoalveolar lavage in acute rat inhalation studies according to TRGS 430. [electronic resource] - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Feb 2007 - 237-43 p. digital

Publication Type: Journal Article

0278-6915

10.1016/j.fct.2006.08.016 doi


Administration, Inhalation
Aerosols
Air Pollutants--toxicity
Air Pollution--legislation & jurisprudence
Animals
Biological Assay
Bronchoalveolar Lavage
Bronchoalveolar Lavage Fluid--chemistry
Cyanates--administration & dosage
Dose-Response Relationship, Drug
Germany
Humidity
Inhalation Exposure--legislation & jurisprudence
Isocyanates
Lung--drug effects
Male
No-Observed-Adverse-Effect Level
Occupational Exposure--legislation & jurisprudence
Rats
Rats, Wistar
Temperature
Toxicity Tests, Acute