Neutralization of ciliary neurotrophic factor reduces astrocyte production from transplanted neural stem cells and promotes regeneration of corticospinal tract fibers in spinal cord injury.

Ishii, Ken

Neutralization of ciliary neurotrophic factor reduces astrocyte production from transplanted neural stem cells and promotes regeneration of corticospinal tract fibers in spinal cord injury. [electronic resource] - Journal of neuroscience research Dec 2006 - 1669-81 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0360-4012

10.1002/jnr.21079 doi


2',3'-Cyclic-Nucleotide Phosphodiesterases--metabolism
Analysis of Variance
Animals
Antibodies--pharmacology
Astrocytes--drug effects
Biotin--analogs & derivatives
Bromodeoxyuridine--metabolism
Cell Count--methods
Cell Differentiation--drug effects
Ciliary Neurotrophic Factor--immunology
Dextrans--metabolism
Embryo, Mammalian
Female
Glial Fibrillary Acidic Protein--metabolism
Intermediate Filament Proteins--metabolism
Nerve Regeneration--drug effects
Nerve Tissue Proteins--metabolism
Nestin
Neurons
Pyramidal Tracts--physiopathology
Rats
Rats, Sprague-Dawley
Spinal Cord Injuries--pathology
Stem Cell Transplantation--methods
Stem Cells--drug effects
Time Factors