Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB.

Xu, Ying

Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB. [electronic resource] - Brain research Nov 2006 - 56-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-8993

10.1016/j.brainres.2006.09.009 doi


Adrenal Glands--anatomy & histology
Analysis of Variance
Animals
Body Weight--drug effects
Brain-Derived Neurotrophic Factor--drug effects
Corticosterone--blood
Curcuma
Curcumin--administration & dosage
Cyclic AMP Response Element-Binding Protein--drug effects
Depressive Disorder--drug therapy
Dose-Response Relationship, Drug
Down-Regulation
Drugs, Chinese Herbal--administration & dosage
Escape Reaction--drug effects
Exploratory Behavior--drug effects
Frontal Lobe--drug effects
Hippocampus--drug effects
Hypothalamo-Hypophyseal System--drug effects
Male
Organ Size
Phosphorylation
Pituitary-Adrenal System--drug effects
RNA, Messenger--analysis
Rats
Rats, Sprague-Dawley
Statistics, Nonparametric
Stress, Psychological--complications