A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice.
Larsen, Kristin E
A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice. [electronic resource] - Brain research Nov 2006 - 1-12 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0006-8993
10.1016/j.brainres.2006.08.079 doi
Analysis of Variance
Animals
Animals, Newborn
Axotomy--methods
Cell Survival--drug effects
Cells, Cultured
Dopamine--metabolism
Dose-Response Relationship, Drug
Glial Cell Line-Derived Neurotrophic Factor--chemistry
Humans
Immunohistochemistry--methods
Male
Mesencephalon--cytology
Mice
Mice, Inbred C57BL
Motor Neurons--drug effects
Neuroblastoma
Neuroprotective Agents--pharmacology
Peptide Fragments--chemistry
Protein Transport--drug effects
Rats
Rats, Sprague-Dawley
Recombinant Proteins--pharmacology
Spinal Cord--cytology
Tetanus Toxin--chemistry
Tyrosine 3-Monooxygenase--metabolism
A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice. [electronic resource] - Brain research Nov 2006 - 1-12 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0006-8993
10.1016/j.brainres.2006.08.079 doi
Analysis of Variance
Animals
Animals, Newborn
Axotomy--methods
Cell Survival--drug effects
Cells, Cultured
Dopamine--metabolism
Dose-Response Relationship, Drug
Glial Cell Line-Derived Neurotrophic Factor--chemistry
Humans
Immunohistochemistry--methods
Male
Mesencephalon--cytology
Mice
Mice, Inbred C57BL
Motor Neurons--drug effects
Neuroblastoma
Neuroprotective Agents--pharmacology
Peptide Fragments--chemistry
Protein Transport--drug effects
Rats
Rats, Sprague-Dawley
Recombinant Proteins--pharmacology
Spinal Cord--cytology
Tetanus Toxin--chemistry
Tyrosine 3-Monooxygenase--metabolism