Desensitization of GABA(B) receptor signaling by formation of protein complexes of GABA(B2) subunit with GRK4 or GRK5.

Kanaide, Masato

Desensitization of GABA(B) receptor signaling by formation of protein complexes of GABA(B2) subunit with GRK4 or GRK5. [electronic resource] - Journal of cellular physiology Jan 2007 - 237-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9541

10.1002/jcp.20863 doi


Animals
Baclofen--pharmacology
Bacterial Proteins--genetics
Blotting, Western
Cell Membrane--metabolism
Cells
Cricetinae
Dose-Response Relationship, Drug
Fluorescence Recovery After Photobleaching
Fluorescence Resonance Energy Transfer
G Protein-Coupled Inwardly-Rectifying Potassium Channels--drug effects
G-Protein-Coupled Receptor Kinase 4
G-Protein-Coupled Receptor Kinase 5
GABA Agonists--pharmacology
Immunoprecipitation
Luminescent Proteins--genetics
Membrane Potentials--drug effects
Microinjections
Oligopeptides
Oocytes--metabolism
Peptides--genetics
Protein Serine-Threonine Kinases--genetics
Protein Subunits--metabolism
Protein Transport
Receptors, GABA-B--drug effects
Recombinant Fusion Proteins--metabolism
Signal Transduction--drug effects
Transfection
Xenopus