Extrapolating from animal studies to the efficacy in humans of a pretreatment combination against organophosphate poisoning.

Levy, Aharon

Extrapolating from animal studies to the efficacy in humans of a pretreatment combination against organophosphate poisoning. [electronic resource] - Archives of toxicology May 2007 - 353-9 p. digital

Publication Type: Journal Article

0340-5761

10.1007/s00204-006-0153-6 doi


Animals
Chemical Warfare Agents--poisoning
Cholinergic Antagonists--administration & dosage
Cyclopentanes--blood
Disease Models, Animal
Dogs
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical--methods
Drug Therapy, Combination
Female
Humans
Infusions, Intravenous
Infusions, Parenteral
Lethal Dose 50
Male
Metabolic Clearance Rate
Organophosphate Poisoning
Organophosphates--administration & dosage
Papio anubis
Poisoning--blood
Pyridostigmine Bromide--blood
Sarin--administration & dosage
Species Specificity
Treatment Outcome