Are dose-finding studies still necessary when targeted therapy is associated with chemotherapy?

Gelibter, Alain J

Are dose-finding studies still necessary when targeted therapy is associated with chemotherapy? [electronic resource] - Journal of clinical oncology : official journal of the American Society of Clinical Oncology Oct 2006 - 4668-9; author reply 4669 p. digital

Publication Type: Comment; Letter

1527-7755

10.1200/JCO.2006.08.3576 doi


Antibiotics, Antineoplastic--pharmacology
Antineoplastic Agents--adverse effects
Capecitabine
Clinical Trials as Topic--methods
Cohort Studies
Data Interpretation, Statistical
Deoxycytidine--analogs & derivatives
Erlotinib Hydrochloride
Fluorouracil--analogs & derivatives
Gastrointestinal Tract--drug effects
Humans
Middle Aged
Neoplasms--drug therapy
Protein Kinase Inhibitors--pharmacology
Quinazolines--pharmacology
Research Design