Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.
Richards, Steven
Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome. [electronic resource] - Bioorganic & medicinal chemistry letters Dec 2006 - 6241-5 p. digital
Publication Type: Journal Article
0960-894X
10.1016/j.bmcl.2006.09.035 doi
11-beta-Hydroxysteroid Dehydrogenase Type 1--antagonists & inhibitors
Carbenoxolone--chemistry
Enzyme Inhibitors--chemical synthesis
Humans
Metabolic Syndrome--drug therapy
Molecular Conformation
Piperazines--chemistry
Sulfonamides--chemistry
Thiazoles--chemistry
Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome. [electronic resource] - Bioorganic & medicinal chemistry letters Dec 2006 - 6241-5 p. digital
Publication Type: Journal Article
0960-894X
10.1016/j.bmcl.2006.09.035 doi
11-beta-Hydroxysteroid Dehydrogenase Type 1--antagonists & inhibitors
Carbenoxolone--chemistry
Enzyme Inhibitors--chemical synthesis
Humans
Metabolic Syndrome--drug therapy
Molecular Conformation
Piperazines--chemistry
Sulfonamides--chemistry
Thiazoles--chemistry