Inhibition of EphA7 up-regulation after spinal cord injury reduces apoptosis and promotes locomotor recovery.

Figueroa, Johnny D

Inhibition of EphA7 up-regulation after spinal cord injury reduces apoptosis and promotes locomotor recovery. [electronic resource] - Journal of neuroscience research Nov 2006 - 1438-51 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0360-4012

10.1002/jnr.21048 doi


Analysis of Variance
Animals
Apoptosis--drug effects
Astrocytes--metabolism
Female
Glial Fibrillary Acidic Protein--metabolism
Immunohistochemistry--methods
In Situ Nick-End Labeling--methods
Membrane Potentials--drug effects
Motor Activity--drug effects
Oligodeoxyribonucleotides, Antisense--pharmacology
Patch-Clamp Techniques--methods
Phosphopyruvate Hydratase--metabolism
RNA, Messenger--biosynthesis
Rats
Rats, Sprague-Dawley
Receptor, EphA7--antagonists & inhibitors
Recovery of Function--drug effects
Reverse Transcriptase Polymerase Chain Reaction--methods
Spinal Cord Injuries--drug therapy
Time Factors
Up-Regulation--drug effects