Intranasal administration of adjuvant-combined recombinant influenza virus HA vaccine protects mice from the lethal H5N1 virus infection.

Asahi-Ozaki, Yasuko

Intranasal administration of adjuvant-combined recombinant influenza virus HA vaccine protects mice from the lethal H5N1 virus infection. [electronic resource] - Microbes and infection Oct 2006 - 2706-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1286-4579

10.1016/j.micinf.2006.07.018 doi


Adjuvants, Immunologic
Administration, Intranasal
Animals
Antibodies, Viral--analysis
Chitin--immunology
Cholera Toxin--immunology
Disease Models, Animal
Female
Hemagglutinin Glycoproteins, Influenza Virus--genetics
Immunity, Mucosal
Immunoglobulin A--analysis
Immunoglobulin G--blood
Influenza A Virus, H5N1 Subtype--immunology
Influenza Vaccines--administration & dosage
Lymphoid Tissue--immunology
Mice
Mice, Inbred BALB C
Microspheres
Nasal Mucosa--immunology
Orthomyxoviridae Infections--prevention & control
Poly I-C--immunology
RNA, Double-Stranded--immunology
Spleen--immunology
Toll-Like Receptors--biosynthesis
Vaccines, Subunit--genetics
Vaccines, Synthetic--genetics