Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo.

Menzel, K

Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo. [electronic resource] - Clinical and experimental immunology Oct 2006 - 169-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0009-9104

10.1111/j.1365-2249.2006.03188.x doi


Animals
Cathepsin B--antagonists & inhibitors
Cathepsin D--antagonists & inhibitors
Cathepsin L
Cathepsins--antagonists & inhibitors
Colitis--drug therapy
Cysteine Endopeptidases--biosynthesis
Cysteine Proteinase Inhibitors--therapeutic use
Dipeptides--therapeutic use
Disease Models, Animal
Female
Gene Expression
Humans
Inflammatory Bowel Diseases--enzymology
Intestinal Mucosa--enzymology
Macrophages--enzymology
Mice
Mice, Inbred BALB C
RNA, Messenger--genetics
Reverse Transcriptase Polymerase Chain Reaction--methods