Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.

Limtrakul, Pornngarm

Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. [electronic resource] - Molecular and cellular biochemistry Feb 2007 - 85-95 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

0300-8177

10.1007/s11010-006-9302-8 doi


ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1
ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-Binding Cassette Transporters--metabolism
Adenosine Triphosphate--metabolism
Antineoplastic Agents--chemistry
Beryllium--metabolism
Cell Line, Tumor
Chlorophyll--analogs & derivatives
Curcumin--analogs & derivatives
Drug Resistance, Multiple--physiology
Drug Resistance, Neoplasm
Etoposide--metabolism
Fluoresceins--metabolism
Fluorescent Dyes--metabolism
Fluorides--metabolism
Humans
Mitoxantrone--metabolism
Molecular Structure
Multidrug Resistance-Associated Proteins--metabolism
Neoplasm Proteins--metabolism
Organic Anion Transporters--metabolism
Rhodamine 123--metabolism
Vinblastine--metabolism