Metabolic activation of chlorpromazine by stimulated human polymorphonuclear leukocytes. Induction of covalent binding of chlorpromazine to nucleic acids and proteins.

Kelder, P P

Metabolic activation of chlorpromazine by stimulated human polymorphonuclear leukocytes. Induction of covalent binding of chlorpromazine to nucleic acids and proteins. [electronic resource] - Chemico-biological interactions 1991 - 15-30 p. digital

Publication Type: Journal Article

0009-2797

10.1016/0009-2797(91)90049-d doi


Biotransformation
Calcimycin--pharmacology
Chlorpromazine--metabolism
Chromatography, High Pressure Liquid
DNA Damage
Humans
In Vitro Techniques
Luminescent Measurements
Neutrophils--metabolism
Nucleic Acids--metabolism
Peroxidase--metabolism
Proteins--metabolism
Tetradecanoylphorbol Acetate--pharmacology