ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of pro-atherogenic lipoproteins and enhanced atherosclerosis.

Joyce, Charles W

ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of pro-atherogenic lipoproteins and enhanced atherosclerosis. [electronic resource] - The Journal of biological chemistry Nov 2006 - 33053-65 p. digital

Publication Type: Journal Article

0021-9258

10.1074/jbc.M604526200 doi


ATP Binding Cassette Transporter 1
ATP-Binding Cassette Transporters--genetics
Animals
Aorta--metabolism
Atherosclerosis--genetics
Biliary Tract--metabolism
Cholesterol--blood
Disease Progression
Feces
Female
Gene Expression Regulation
Hemostasis
Humans
Intestinal Mucosa--metabolism
Lipid Metabolism
Lipoproteins--metabolism
Liver--metabolism
Mice
Mice, Transgenic
Oligonucleotide Array Sequence Analysis
Organ Specificity
Receptors, LDL--deficiency
Sterols--metabolism