An altered peptide ligand for naïve cytotoxic T lymphocyte epitope of TRP-2(180-188) enhanced immunogenicity.

Tang, Yan

An altered peptide ligand for naïve cytotoxic T lymphocyte epitope of TRP-2(180-188) enhanced immunogenicity. [electronic resource] - Cancer immunology, immunotherapy : CII Mar 2007 - 319-29 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0340-7004

10.1007/s00262-006-0195-x doi


Amino Acid Substitution--immunology
Animals
Binding Sites
Binding, Competitive
Brefeldin A--pharmacology
Cell Line, Tumor
Dendritic Cells
Dose-Response Relationship, Immunologic
Epitopes, T-Lymphocyte--drug effects
HLA-A Antigens--drug effects
HLA-A2 Antigen
Humans
Interferon-gamma--biosynthesis
Intramolecular Oxidoreductases--immunology
Leukocytes, Mononuclear--immunology
Ligands
Membrane Proteins--chemistry
Mice
Mice, Transgenic
Models, Molecular
Peptide Fragments--chemistry
Reference Values
Structure-Activity Relationship
T-Lymphocytes, Cytotoxic--drug effects