Attenuation of collagen production with small interfering RNA of SPARC in cultured fibroblasts from the skin of patients with scleroderma.

Zhou, Xiaodong

Attenuation of collagen production with small interfering RNA of SPARC in cultured fibroblasts from the skin of patients with scleroderma. [electronic resource] - Arthritis and rheumatism Aug 2006 - 2626-31 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0004-3591

10.1002/art.21973 doi


Activin Receptors, Type I--genetics
Biomarkers--metabolism
Cells, Cultured
Collagen Type I--metabolism
Collagen Type II--metabolism
Connective Tissue Growth Factor
Female
Fibroblasts--metabolism
Gene Expression--genetics
Humans
Immediate-Early Proteins--genetics
Intercellular Signaling Peptides and Proteins--genetics
Male
Osteonectin--genetics
Protein Serine-Threonine Kinases
RNA, Small Interfering--genetics
Receptor, Transforming Growth Factor-beta Type I
Receptors, Transforming Growth Factor beta--genetics
Scleroderma, Systemic--metabolism
Skin
Transfection