CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway.

Ardyanto, Tonang Dwi

CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway. [electronic resource] - International journal of oncology Sep 2006 - 549-55 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1019-6439


Antimutagenic Agents--pharmacology
Apoptosis--drug effects
Caspase 9
Caspases--metabolism
Cell Cycle--drug effects
Cell Hypoxia
Cell Proliferation--drug effects
Class I Phosphatidylinositol 3-Kinases
Cobalt--pharmacology
Cyclin B--metabolism
Cyclin B1
Cyclin-Dependent Kinase Inhibitor p27--metabolism
Humans
Hypoxia-Inducible Factor 1--metabolism
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation--drug effects
Proto-Oncogene Proteins c-akt--metabolism
Proto-Oncogene Proteins c-bcl-2--metabolism
S-Phase Kinase-Associated Proteins--metabolism
Signal Transduction--drug effects
Stomach Neoplasms--drug therapy
Tumor Cells, Cultured
bcl-2-Associated X Protein--metabolism
bcl-X Protein--metabolism