Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity.

Kocak, Ergun

Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity. [electronic resource] - Cancer research Jul 2006 - 7276-84 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

0008-5472

10.1158/0008-5472.CAN-05-2128 doi


Animals
Antibodies, Monoclonal--administration & dosage
Antigens, CD--immunology
Antigens, Differentiation--immunology
Antineoplastic Combined Chemotherapy Protocols--immunology
Autoimmunity--immunology
CD8-Positive T-Lymphocytes--immunology
CTLA-4 Antigen
Colonic Neoplasms--immunology
Female
Humans
Immunization, Passive--methods
Mice
Mice, Inbred C57BL
Receptors, Nerve Growth Factor--immunology
Receptors, Tumor Necrosis Factor--immunology
T-Lymphocytes, Regulatory--immunology
Tumor Necrosis Factor Receptor Superfamily, Member 9