The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells.
Gomez, Dennis
The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells. [electronic resource] - Cancer research Jul 2006 - 6908-12 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0008-5472
10.1158/0008-5472.CAN-06-1581 doi
Cell Line
DNA--biosynthesis
G-Quadruplexes
Green Fluorescent Proteins--genetics
Humans
Kidney--cytology
Nuclear Proteins--metabolism
Oxazoles--pharmacology
Protein Binding
Recombinant Fusion Proteins--genetics
Shelterin Complex
TATA Box Binding Protein-Like Proteins--metabolism
Telomere--genetics
Telomere-Binding Proteins--antagonists & inhibitors
Telomeric Repeat Binding Protein 2
Transfection
The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells. [electronic resource] - Cancer research Jul 2006 - 6908-12 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0008-5472
10.1158/0008-5472.CAN-06-1581 doi
Cell Line
DNA--biosynthesis
G-Quadruplexes
Green Fluorescent Proteins--genetics
Humans
Kidney--cytology
Nuclear Proteins--metabolism
Oxazoles--pharmacology
Protein Binding
Recombinant Fusion Proteins--genetics
Shelterin Complex
TATA Box Binding Protein-Like Proteins--metabolism
Telomere--genetics
Telomere-Binding Proteins--antagonists & inhibitors
Telomeric Repeat Binding Protein 2
Transfection