Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects.

Mortellaro, Alessandra

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects. [electronic resource] - Blood Nov 2006 - 2979-88 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-4971

10.1182/blood-2006-05-023507 doi


Adenosine Deaminase--deficiency
Animals
Antibody Formation
B-Lymphocytes--immunology
Bone Marrow Transplantation--immunology
Flow Cytometry
Gene Transfer Techniques
Genetic Vectors
Killer Cells, Natural--immunology
Lentivirus--genetics
Lymphocyte Activation
Lymphocyte Count
Mice
Mice, Knockout
Mice, Transgenic
Spleen--immunology