Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts.

Wang, Youngqing

Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. [electronic resource] - Arthritis and rheumatism Jul 2006 - 2271-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0004-3591

10.1002/art.21948 doi


Azacitidine--pharmacology
Cells, Cultured
Collagen Type I--genetics
CpG Islands--genetics
DNA Methylation
DNA Modification Methylases--antagonists & inhibitors
Epigenesis, Genetic--genetics
Fibroblasts--drug effects
Gene Expression Regulation--drug effects
Genes, Suppressor--physiology
Histone Deacetylase Inhibitors
Histone Deacetylases--physiology
Humans
Hydroxamic Acids--pharmacology
Phenotype
Promoter Regions, Genetic--physiology
Proto-Oncogene Protein c-fli-1--genetics
Scleroderma, Systemic--genetics
Signal Transduction--genetics
Skin--drug effects
Transfection