Ex vivo-activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: mechanism of antibody-dependent cellular cytotoxicity and impact of human serum.

Lefebvre, Marie-Laure

Ex vivo-activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: mechanism of antibody-dependent cellular cytotoxicity and impact of human serum. [electronic resource] - Journal of immunotherapy (Hagerstown, Md. : 1997) - 388-97 p. digital

Publication Type: Journal Article

1524-9557

10.1097/01.cji.0000203081.43235.d7 doi


Antibodies, Monoclonal--pharmacology
Antibodies, Monoclonal, Murine-Derived
Antibody-Dependent Cell Cytotoxicity--immunology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Complement System Proteins--physiology
Cytotoxicity, Immunologic
Flow Cytometry--methods
Humans
Immunoglobulin G--blood
Leukemia, Lymphocytic, Chronic, B-Cell--immunology
Macrophage Activation
Macrophages--immunology
Receptors, IgG--physiology
Rituximab
Serum--physiology