Expression of the cytoplasmic domain of beta1 integrin induces apoptosis in adult rat ventricular myocytes (ARVM) via the involvement of caspase-8 and mitochondrial death pathway.

Menon, Bindu

Expression of the cytoplasmic domain of beta1 integrin induces apoptosis in adult rat ventricular myocytes (ARVM) via the involvement of caspase-8 and mitochondrial death pathway. [electronic resource] - Basic research in cardiology Nov 2006 - 485-93 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0300-8428

10.1007/s00395-006-0602-7 doi


Animals
Apoptosis--physiology
BH3 Interacting Domain Death Agonist Protein--metabolism
Caspase 8--metabolism
Cells, Cultured
Cytochromes c--metabolism
Integrin beta1--genetics
Male
Membrane Potential, Mitochondrial--physiology
Mice
Mitochondria, Heart--physiology
Myocytes, Cardiac--pathology
Protein Structure, Tertiary--genetics
Rats
Rats, Sprague-Dawley
Receptors, Adrenergic, beta--physiology
Receptors, Interleukin-2--physiology